Clinical Trial: Prophylactic Antibiotic Duration in Head and Neck Cancer Surgery: A Pragmatic, Open-Label, Randomized Superiority Trial (PROTECT-HN Trial)

U.S., Oct. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07851857) titled 'Prophylactic Antibiotic Duration in Head and Neck Cancer Surgery: A Pragmatic, Open-Label, Randomized Superiority Trial (PROTECT-HN Trial)' on Sept. 25.

Brief Summary: The goal of this clinical trial is to learn whether giving antibiotics for 7 days after surgery, instead of the usual 24 hours, lowers the chance of wound infection in adults having major surgery for mouth or throat cancer. This includes operations that rebuild the area with tissue taken from another part of the body (free-flap reconstruction).

The main question it aims to answer is:

Does a 7-day course of antibiotics after surgery lower the number of patients who ge...