U.S., April 17 -- ClinicalTrials.gov registry received information related to the study (NCT07533643) titled 'Preoperative Topical Lidocaine Versus Intravenous Fentanyl to Obtund the Stress of Intubation Under Anesthesia.' on April 10.

Brief Summary: To compare the effectiveness of preoperative combined topical airway anesthesia consisting of nebulised, mouth rinsing and gargling with lidocaine versus intravenous fentanyl to prevent the stress of endotracheal intubation by direct laryngoscopy under general anesthesia.

Study Start Date: Aug. 01, 2025

Study Type: INTERVENTIONAL

Condition: Hemodynamics After Endotracheal Intubation

Intervention: DRUG: topical lidocaine

topical lidocaine nebulized for 10 min + mouth rinsing and gargling...