U.S., March 12 -- ClinicalTrials.gov registry received information related to the study (NCT07464886) titled 'Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth' on July 28, 2025.
Brief Summary: The primary goal is to investigate to what extent changes in glutamate and glutathione modulation and functional integration between brain networks associated with emotion and attention regulation are associated with treatment response in mildly depressed youth.
Study Start Date: Feb. 26
Study Type: INTERVENTIONAL
Condition:
Mild Depression
Intervention:
DRUG: N-acetylcysteine
N-acetylcysteine 2400 mg/d
BEHAVIORAL: Mindfulness-based cognitive therapy
Mindfulness-based cognitive therapy
DRUG: Placebo
Placebo capsu...