U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07845604) titled 'Precision Depression Adalimumab Trial' on Sept. 22.
Brief Summary: The goal of this clinical trial is to learn if the anti-inflammatory medication adalimumab improves depressive symptoms in adults with Major Depressive Disorder (MDD) who are already taking the anti-depressant medication Lexapro (escitalopram).
The main questions it aims to answer are:
1. Does adalimumab improve the symptoms of some patients with MDD who are already taking an anti-depressant?
2. What characteristics predict for whom adalimumab has anti-depressant properties.
Researchers will compare adalimumab to a placebo (a look-alike substance that contains n...