Clinical Trial: Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment

U.S., Oct. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07885085) titled 'Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment' on Oct. 13.

Brief Summary: Mild cognitive impairment (MCI) affects a substantial proportion of older adults undergoing major surgery and may alter pain processing, pain experience, and opioid use after surgery. This prospective observational cohort study will compare older adults with MCI and cognitively intact older adults undergoing major orthopedic and complex spine procedures. Participants will undergo preoperative assessment of cognitive function, quantitative sensory testing, heart rate variability, clinical pain, and biomarkers associated ...