U.S., May 21 -- ClinicalTrials.gov registry received information related to the study (NCT07599865) titled 'Periprosthetic Joint Infection Bubble Study' on May 14.
Brief Summary: Patients with an infected knee replacement will receive their standard of care surgical treatment of the infection, with and without additional ultrasound microbubble treatment (randomly divided 50/50 in the active and control groups). Subjects in the active group will receive a local bolus injection of antibiotics and ultrasound-active microbubbles within 24 hours of their revision surgery. The fundamental hypothesis is that a decrease in re-infection rates of at least 24% can be achieved in the active group relative to controls.
Study Start Date: June, 2026
St...