U.S., March 3 -- ClinicalTrials.gov registry received information related to the study (NCT07441824) titled 'Pancreatic Enzyme Replacement in Acute Necrotizing Pancreatitis' on Feb. 15.
Brief Summary: In this multicenter, double blinded, placebo-controlled, 1:1 parallel group RCT, the investigators propose to evaluate the impact of pancreatic exocrine replacement therapy on patients with acute necrotizing pancreatitis (ANP). The investigators will include patients of 18-60yrs age and both genders with >50% pancreatic parenchymal necrosis and at least 5% loss of body weight.
The primary outcome measure is percent change in body weight at 3 months after enrolment. The intervention will include pancreatic enzyme consisting of 25000 IU of lip...