Clinical Trial: Oxiris in Septic AKI

U.S., June 12 -- ClinicalTrials.gov registry received information related to the study (NCT07641660) titled 'Oxiris in Septic AKI' on March 03.

Brief Summary: Sepsis is a leading cause of acute kidney injury (AKI) in critically ill patients, with sepsis-associated AKI accounting for approximately 50% of all AKI cases in the intensive care unit. The pathophysiology of septic AKI involves a complex interplay of inflammation, endothelial dysfunction, and microvascular injury, leading to impaired renal perfusion and tubular damage. Despite advances in critical care, septic AKI remains associated with high mortality rates and significant risk of progression to chronic kidney disease.

Continuous renal replacement therapy (CRRT) is the standard ...