Clinical Trial: Optimizing Tumor-Infiltrating Lymphocyte (TIL) Harvest Site and Patient Selection With CD8-PET Imaging in Patients With

U.S., Sept. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07819474) titled 'Optimizing Tumor-Infiltrating Lymphocyte (TIL) Harvest Site and Patient Selection With CD8-PET Imaging in Patients With' on Sept. 10.

Brief Summary: To find out if the amount of CD8 immune cells at the place where TIL cells are collected is linked to how well a patient responds to treatment.

Study Start Date: Feb. 18, 2027

Study Type: INTERVENTIONAL

Condition: Tumor Infiltrating Lymphocyte CD8-PET Advanced Melanoma

Intervention: DRUG: Crefmirlimb

Given by Iv

DEVICE: PET/CT imaging

An additional excision, for research purposes only, will be performed from the site with the highest CD8 PET SUVmean as long as it is a dermal, ...