U.S., Nov. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07923318) titled 'Optimal Treatment Strategy for Spontaneous Bacterial Peritonitis' on Oct. 28.
Brief Summary: Spontaneous bacterial peritonitis (SBP) is a serious infection that occurs in patients with liver cirrhosis and ascites and is associated with substantial morbidity and mortality. Current clinical practice often includes follow-up paracentesis approximately 48 hours after starting antibiotic treatment to assess the change in the ascitic fluid polymorphonuclear leukocyte (PMN) count. However, it remains uncertain whether routine follow-up paracentesis improves clinical outcomes compared with a strategy based primarily on clinical response.
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