Clinical Trial: Optimal Allogeneic PRP Concentration for Oocyte In Vitro Maturation in Women With PCOS

U.S., April 8 -- ClinicalTrials.gov registry received information related to the study (NCT07514234) titled 'Optimal Allogeneic PRP Concentration for Oocyte In Vitro Maturation in Women With PCOS' on March 23.

Brief Summary: In vitro maturation is a long-studied technique used to obtain mature oocytes outside the human body. However, this method can increase the risk of ovarian hyperstimulation syndrome (OHSS), particularly in patients with polycystic ovarian syndrome (PCOS). Culture media supplemented with platelet-rich plasma (PRP) has previously shown promise for improving oocyte maturation. This study examined the potential utility of allogeneic PRP supplementation to increase the maturation of germinal vesicle (GV)-stage oocytes colle...