U.S., March 19 -- ClinicalTrials.gov registry received information related to the study (NCT07479446) titled 'Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery' on Feb. 11.
Brief Summary: This single-center, double-blind, randomized controlled trial aims to determine whether oliceridine for patient-controlled intravenous analgesia (PCIA) can significantly reduce the incidence of postoperative nausea, an opioid-related adverse reaction, compared to sufentanil PCIA in patients undergoing cerebellopontine angle (CPA) region surgery. A secondary objective is to compare the postoperative analgesic effects between the two drugs. The study plans to enroll 174 patients (with a calculated sample size of 164 pl...