U.S., Oct. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07867353) titled 'Natural History of Injectable Permanent Synthetic Filler Disease' on Oct. 05.
Brief Summary: Injectable permanent synthetic filler disease is characterized by heterogeneous local and systemic manifestations that may emerge years after filler injection. Although inflammatory reactions, migration, foreign-body granulomas, adipose tissue injury, fat necrosis, and fibrosis have been individually described, the temporal clinicopathologic evolution of the disease remains poorly characterized.
This prospective observational cohort study aims to characterize the natural history of disease associated with injectable permanent synthetic fill...