U.S., Feb. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07416201) titled 'Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy' on Feb. 14.
Brief Summary: Background:
Down syndrome is a genetic disorder that can cause heart defects and other problems in the body. People with Down syndrome are more likely to have infections, autoimmunity, and blood diseases. Some may need surgery to treat congenital heart problems. During this surgery, doctors sometimes remove part of the thymus. The thymus is an organ that plays a role in immune function. People who have had part of their thymus removed may get sick more often than others do.
Objective:
T...