U.S., April 2 -- ClinicalTrials.gov registry received information related to the study (NCT07505745) titled 'MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity' on March 14.

Brief Summary: This Phase 2a study evaluates whether 12 weeks of treatment with investigational MOTS-c improves insulin sensitivity compared with placebo in adults with prediabetes and overweight/obesity.

Participants are randomized 1:1 to MOTS-c or placebo, receive standardized lifestyle counseling, and are followed for safety through Week 16.

Study Start Date: Feb. 02

Study Type: INTERVENTIONAL

Condition: Prediabetes Insulin Resistance Overweight/Obesity

Intervention: DRUG: MOTS-c (MDP)

Drug: MOTS-c (MDP)

DRUG: Placebo...