U.S., July 2 -- ClinicalTrials.gov registry received information related to the study (NCT07680010) titled 'Model Early Immunologic Stages of Pediatric Hematological Pre-lupus' on June 25.
Brief Summary: Immunologic thrombocytopenic purpura (ITP) in children is a pre-lupus condition if associated with the presence of anti-nuclear antibodies (ANA), providing a unique model for understanding the natural history of autoimmunity, particularly that of systemic lupus erythematosus (SLE). We will describe the shared and/or unique immunological pathways involved at diagnosis in 70 children with ITP and in 20 children with SLE, and compare them between ITP-ANA- (more often transient), ITP-ANA+ (pre-lupus condition, more often persistent) and SLE
S...