U.S., Feb. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07393711) titled 'Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy' on Jan. 30.
Brief Summary: Kidney stone recurrence, particularly infection-related stones, remains a significant clinical problem after percutaneous nephrolithotripsy (PCNL). Bacterial colonization and persistent infection are recognized contributors to stone recurrence.
This study evaluates the effectiveness of intrarenal dioxidine instillation as a metaphylactic measure to reduce recurrence of infection-related kidney stones following PCNL. Patients undergoing PCNL will receive standard treatment, with or without adjunctive intrarenal dioxidine administra...