Clinical Trial: Medium Cut-Off and High-Flux Membranes on Mineral and Bone Metabolism in Hemodialysis Patients

U.S., July 7 -- ClinicalTrials.gov registry received information related to the study (NCT07685223) titled 'Medium Cut-Off and High-Flux Membranes on Mineral and Bone Metabolism in Hemodialysis Patients' on June 24.

Brief Summary: This study aims to compare the effects of medium cut-off (MCO) and high-flux hemodialysis membranes on mineral and bone metabolism biomarkers in patients receiving maintenance hemodialysis. Chronic kidney disease-mineral and bone disorder (CKD-MBD) is characterized by disturbances in biomarkers such as fibroblast growth factor-23 (FGF-23) and sclerostin, which are associated with bone turnover, vascular calcification, and adverse clinical outcomes.

This is a single-center, prospective, randomized, open-label, tw...