Clinical Trial: Long-term Outcomes After Percutaneous Patent Foramen Ovale Closure (Severance PFO Registry)

U.S., July 24 -- ClinicalTrials.gov registry received information related to the study (NCT07724171) titled 'Long-term Outcomes After Percutaneous Patent Foramen Ovale Closure (Severance PFO Registry)' on July 13.

Brief Summary: Patent foramen ovale (PFO) is a congenital interatrial communication present in about one quarter of the general population and is recognized as a major cause of cryptogenic stroke. Percutaneous PFO closure reduces recurrent stroke, but a residual right-to-left shunt persists in 20 to 40 percent of patients after device implantation. Long-term data on device performance, the evolution of residual shunt over time, new-onset atrial fibrillation and other prognostic factors remain limited.

This single-center registry...