U.S., Nov. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07922759) titled 'Lidocaine Infiltration and Neuroimmunomodulation in Head and Neck Cancer Surgery' on Nov. 02.
Brief Summary: This study aims to investigate whether different doses of locally infiltrated lidocaine affect inflammation, neurological biomarkers, and cognitive function in patients undergoing major head and neck cancer surgery.
Major head and neck cancer surgery can cause substantial physical stress, inflammation, and changes in cognitive function after surgery. Lidocaine is a commonly used local anesthetic that may also have anti-inflammatory and protective effects on the nervous system. However, little is known about whether the dose o...