Clinical Trial: KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided Antibiotic Initiation With Using Absolute Procalcitonin Values in Reducing Unnecessary Antibiotic Use in Critically Ill Patients

U.S., Oct. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07211620) titled 'KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided Antibiotic Initiation With Using Absolute Procalcitonin Values in Reducing Unnecessary Antibiotic Use in Critically Ill Patients' on Sept. 21.

Brief Summary: The study aims to compare the efficacy and safety of an absolute procalcitonin (PCT) value-guided antibiotic initiation protocol and a protocol using the kinetics of PCT (the difference between the actual and the previous day value) in hemodynamically stable critically ill patients with suspected new-onset infection on admission or during ICU stay.

The main question it aims ...