U.S., March 19 -- ClinicalTrials.gov registry received information related to the study (NCT07481370) titled 'Isotretinoin vs hCG for Male Infertility Due to Low or Absent Sperm' on March 13.

Brief Summary: This study compares two medical treatments to see how well they improve sperm production in men with infertility due to low sperm counts (oligospermia) or no sperm in the semen due to non-obstructive causes (nonobstructive azoospermia). Some men with these conditions have limited nonsurgical treatment options, and current therapies do not work for everyone.

Participants in this study will be adult men ages 19 to 50 who have been diagnosed with oligospermia or nonobstructive azoospermia and do not have a correctable cause for infertilit...