Clinical Trial: Investigation of the Treatment of Patients With Mitochondrial Defects by Assisted Reproductive Technology

U.S., Nov. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07911306) titled 'Investigation of the Treatment of Patients With Mitochondrial Defects by Assisted Reproductive Technology' on Jan. 25.

Brief Summary: Mitochondria are important organelles that generate energy (ATP) in human and mammalian cells. Currently, there are more than 50 kinds of diseases known to be related to mitochondrial defects in Taiwan. The incidence of mitochondrial diseases is very rare, about 1/5,000 to 1/10,000. The abundancy of mitochondria riches to 100,000 DNA copies in one oocyte, and the threshold of DNA mutation rate to cause pathogenicity is usually greater than 70%. Since mitochondria are inherited maternally, the pathogeni...