U.S., Nov. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07935460) titled 'Infection Rate With Intramedullary Interlocking Nail Versus Plate Fixation in Open Tibial Fractures' on Nov. 08.
Brief Summary: Open fractures of the tibia are at risk of infection because the injury damages the surrounding soft tissues. This study will compare the frequency of postoperative infection in patients with Gustilo-Anderson type I and II open tibial shaft fractures treated with intramedullary interlocking nail (ILN) fixation or plate fixation after three days of intravenous prophylactic antibiotic therapy.
A total of 170 patients aged 18-60 years will be included and randomly allocated into two groups of 85 patients each...