U.S., June 17 -- ClinicalTrials.gov registry received information related to the study (NCT07652203) titled 'Impact of Propranolol on the Prognosis of Patients With Decompensated Cirrhosis and MELD Score > 9' on June 11.

Brief Summary: Non selective beta blockers (NSBBs), such as propranolol and nadolol, are mainstay therapies for portal hypertension in cirrhosis, but their efficacy and safety vary depending on the stage of the disease. Emerging evidence suggests that NSBBs may worsen the prognosis of advanced cirrhosis, especially in patients with a model for end-stage liver disease (MELD) score of >9. The purpose of this randomized controlled trial is to evaluate the effects of the use of propranolol as recommended by the guideline on th...