U.S., May 7 -- ClinicalTrials.gov registry received information related to the study (NCT07570433) titled 'HORUS-Cytomegalovirus Open Proof-of-concept Exploratory Trial' on April 23.
Brief Summary: Cytomegalovirus (CMV) remains a significant cause of morbidity and mortality following organ transplantation.
Cell-mediated immunity plays a crucial role in controlling CMV replication after transplantation. Immune monitoring involves the use of immune biomarkers to dynamically estimate the risk of CMV replication. This approach allows for the individualization of preventive and therapeutic strategies, improving patient outcomes.
The HORUS-COPE trial is designed to assess the effect of immune modulation on CMV replication kinetics and to explo...