U.S., June 30 -- ClinicalTrials.gov registry received information related to the study (NCT07672977) titled 'Home-Based Closed-Loop Auditory Stimulation to Enhance Slow-Wave Activity in MCI Due to Alzheimer's Disease: A Proof-of-Concept Study' on June 15.
Brief Summary: This proof-of-concept study explores whether long-term home-based closed-loop auditory stimulation during sleep enhances slow-wave activity (SWA) and yields preliminary efficacy signals in patients with amnestic mild cognitive impairment due to Alzheimer's disease (MCI-AD), confirmed by cerebrospinal fluid (CSF) biomarkers or positron emission tomography (PET).
The intervention is self-administered at participants' homes over an initial treatment period of 3 months, follow...