U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07779486) titled 'High- vs Standard-Dose Intravenous Magnesium for Acute Headache' on May 19.

Brief Summary: Headache is one of the most common reasons for consultation in emergency departments and represents a significant cause of disability, particularly in patients with migraine and other primary headache disorders. Despite the availability of several analgesic treatments, including nonsteroidal anti-inflammatory drugs and paracetamol, pain relief is often incomplete, and a proportion of patients require additional rescue therapy.

Magnesium sulfate has emerged as a potential therapeutic option in acute headache due to its role in modulating neuro...