U.S., March 12 -- ClinicalTrials.gov registry received information related to the study (NCT07465172) titled 'GDF-15 and Its Relationship With Treatment-related ADverse Events in Breast Cancer' on Feb. 26.
Brief Summary: GRADE is trying to find out if there is a link between a hormone called GDF-15 and the side effects that people can experience when taking T-DXd.
GDF-15 can be measured in the blood. GDF-15 levels in the blood will go up when the body is stressed under certain conditions, including breast cancer. There is a link between high GDF-15 levels and the nausea and vomiting experienced with "morning sickness" in pregnancy. It has also been shown that GDF-15 levels will go up with the use of other types of chemotherapy that are kn...