U.S., Sept. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07832773) titled 'FOUR-Based Modification of ICU Severity Scores' on Sept. 16.

Brief Summary: The goal of this observational study is to evaluate whether the Full Outline of UnResponsiveness (FOUR) score can replace the Glasgow Coma Scale (GCS) as the neurologic component of established intensive care unit (ICU) severity scoring systems and to derive and validate modified APACHE, SAPS, MODS, LODS, and SOFA models incorporating the FOUR score in critically ill adult patients.

The main questions it aims to answer are:

Does replacing the GCS with the FOUR score provide comparable or improved discrimination for in-hospital mortality across established...