U.S., July 22 -- ClinicalTrials.gov registry received information related to the study (NCT07717060) titled 'Extracellular Vesicle Dynamics Predicting Vascular Complications and Treatment Response in Systemic Sclerosis' on July 09.
Brief Summary: Systemic sclerosis is a multisystem autoimmune disease characterized by vascular dysfunction, immune dysregulation, and progressive tissue fibrosis. Cardiopulmonary complications and peripheral vascular involvement are the principal causes of disability and mortality.
Extracellular vesicles (EVs) have emerged as key mediators of paracrine intercellular communication. Preclinical studies further suggest that EVs mediate long-range inter-organ communication through the circulation. However, the ina...