U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07440368) titled 'Enterocyte Injury and Acute Gastrointestinal Dysfunction in Critical Illness' on Feb. 10.
Brief Summary: Acute gastrointestinal injury (AGI) is a common but not fully understood organ dysfunction in critically ill patients. Current AGI grading systems rely primarily on clinical presentation and feeding tolerance, which are inherently subjective and may not accurately reflect the underlying biological severity of intestinal damage.
Intestinal fatty acid-binding protein (I-FABP) is a protein expressed almost exclusively in the cytoplasm of mature small intestinal epithelial cells. In cases of ischemia, inflammation, or mechanical inj...