U.S., Dec. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07256743) titled 'Efficacy of SALI-10 Oral Probiotics in Experimental Gingivitis' on Sept. 23.
Brief Summary: Gingivitis is among the most prevalent oral diseases worldwide, affecting an estimated 50-90% of adults. It is a reversible condition primarily caused by microbial plaque accumulation on teeth and gingival surfaces, which triggers inflammation. Standard care emphasizes plaque reduction through oral hygiene, and research shows gingivitis can be reversed once hygiene resumes. The classic experimental gingivitis (EG) model developed in 1965 by Loe and Silness demonstrated the direct link between plaque buildup and gingival inflammation, further c...