Clinical Trial: Efficacy and Safety of Piclosept in the Complex Treatment of Neonatal Dacryocystitis

U.S., Oct. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07875517) titled 'Efficacy and Safety of Piclosept in the Complex Treatment of Neonatal Dacryocystitis' on Aug. 25.

Brief Summary: This single-center, prospective, randomized, controlled, assessor-blinded study will evaluate the efficacy and safety of Piclosept(R) ophthalmic solution as an adjunct to standardized lacrimal sac massage in children aged 1 to 12 months with neonatal dacryocystitis. Participants will be randomized in a 1:1:1 ratio to standardized lacrimal sac massage alone, massage plus preservative-free levofloxacin, or massage plus Piclosept(R). The primary outcome is clinical success on Day 14, defined as complete absence of purulent-m...