Clinical Trial: Efficacy and Safety of CD7 CAR-T in Newly Diagnosed High-Risk T-LBL/ALL

U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT07476027) titled 'Efficacy and Safety of CD7 CAR-T in Newly Diagnosed High-Risk T-LBL/ALL' on March 12.

Brief Summary: This study is an open, single-center, prospective clinical trial, with newly diagnosed high-risk T-LBL/ALL patients as the subjects. It plans to enroll 10 subjects. All patients will undergo lymphocyte collection during the CR1 remission period, followed by the preparation and reinfusion of CD7 CAR-T cells. Adverse reactions will be followed up and observed, and relevant data on treatment efficacy will be collected to evaluate the safety, efficacy, and cell metabolic kinetics characteristics of CAR-T cell therapy for the patients. ...