U.S., March 28 -- ClinicalTrials.gov registry received information related to the study (NCT07495163) titled 'Effect of taVNS on Perioperative Anxiety in Major Abdominal Surgery' on March 17.

Brief Summary: It is reported that over 50% of patients undergoing major abdominal surgery experience perioperative anxiety, which often triggers a vicious cycle of "anxiety-pain-gastrointestinal dysfunction" and significantly hinders postoperative recovery. Existing pharmacological and psychological interventions are limited by adverse effects such as respiratory depression, paralytic ileus, and poor patient compliance. While transcutaneous auricular vagus nerve stimulation (taVNS) has shown promise as a non-invasive neuromodulation technique for chr...