U.S., March 28 -- ClinicalTrials.gov registry received information related to the study (NCT07496502) titled 'Effect of Oral Microbiota on MDRO Decolonization' on March 18.

Brief Summary: Randomized, placebo-controlled trial to evaluate the safety and efficacy of oral intestinal microbiota capsules for decolonizing multidrug-resistant organisms (MDROs) and Clostridioides difficile in patients requiring prolonged antibiotic therapy. The primary outcome was clearance of pre-existing MDROs or C. difficile from stool 14 days post-intervention. Secondary outcomes included adverse events, hospitalization rates, and need for additional antibiotics during 30-day follow-up.

Study Start Date: March 31, 2022

Study Type: INTERVENTIONAL

Condition: ...