Clinical Trial: Effect of Omeprazole on Gut Microbiota in Adults With Obesity and GERD

U.S., Oct. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07850960) titled 'Effect of Omeprazole on Gut Microbiota in Adults With Obesity and GERD' on Sept. 24.

Brief Summary: This randomized, open-label, parallel-group study will evaluate the effect of short-term omeprazole therapy on gut and oral microbiota in adults aged 50-65 years with obesity and symptomatic gastroesophageal reflux disease. Participants will be randomized 1:1 to receive omeprazole 20 mg once daily for 14 days plus standard non-pharmacological recommendations for gastroesophageal reflux disease, or standard non-pharmacological recommendations alone. Clinical and laboratory assessments will be performed at baseline and after 14 days. Sto...