U.S., Oct. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07905495) titled 'Early Outcome of Simultaneous Bilateral Total Knee Replacement With and Without Tourniquet' on Oct. 23.
Brief Summary: This randomized controlled trial compared early outcomes after replacement of both knees during the same operation, with and without tourniquet use. A tourniquet was an inflatable cuff placed around the upper thigh and tightened during surgery to temporarily restrict blood flow. The study tested the hypothesis that tourniquet use would reduce blood loss during and after surgery, preserve hemoglobin levels, and reduce early postoperative pain. Hemoglobin was the protein in red blood cells that carried oxygen.
The st...