Clinical Trial: Dopamine Versus Epinephrine for Pediatric Fluid-Refractory Hypotensive Septic Shock

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07775001) titled 'Dopamine Versus Epinephrine for Pediatric Fluid-Refractory Hypotensive Septic Shock' on Aug. 15.

Brief Summary: This randomized clinical trial was conducted to compare dopamine with epinephrine as the first vasoactive treatment in children aged 2 to 12 years with fluid-refractory hypotensive septic shock. Children who remained hypotensive with signs of poor tissue perfusion after receiving standardized intravenous fluid resuscitation were enrolled and randomly assigned in a 1:1 ratio to receive either dopamine or epinephrine. The study was designed to determine whether epinephrine resulted in a higher rate of shock reversal within t...