Clinical Trial: Diagnostic Yield of ACTG2 and FLNA Gene Assessment in Adult Patients With Idiopathic Chronic Intestinal Pseudo-Obstruction and Reduced or Absent Distal Esophageal Contractility

U.S., March 5 -- ClinicalTrials.gov registry received information related to the study (NCT07448753) titled 'Diagnostic Yield of ACTG2 and FLNA Gene Assessment in Adult Patients With Idiopathic Chronic Intestinal Pseudo-Obstruction and Reduced or Absent Distal Esophageal Contractility' on Feb. 25.

Brief Summary: To assess the diagnostic yield of Sanger sequencing for ACTG2 and FLNA genes evaluation on blood or saliva sample in patients with idiopathic CIPO in which high-resolution esophageal manometry (HRM) shows reduced (DCI <450 mmHg*s*cm) or absent distal esophageal contractility.

Study Start Date: Sept. 17, 2025

Study Type: OBSERVATIONAL

Condition: Pseudo Obstruction

Recruitment Status: ENROLLING_BY_INVITATION

Sponsor: Marina Col...