Clinical Trial: Diagnostic Accuracy of The Water Immersion Wrinkle Test for Small Fiber Neuropathy

U.S., Dec. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07255573) titled 'Diagnostic Accuracy of The Water Immersion Wrinkle Test for Small Fiber Neuropathy' on Nov. 20.

Brief Summary: Small-fiber neuropathy (SFN) affects A-delta and C fibers and commonly presents with sensory symptoms and dysautonomia. Confirmation often relies on specialized tests such as quantitative sensory testing (QST) and sympathetic skin response (SSR). This prospective, single-center observational diagnostic-accuracy study will estimate the performance of the Water-Immersion Wrinkle Test (WIWT) for detecting SFN in adults evaluated by a neuromuscular service. The composite reference standard is specialist clinical assessment plus ...