U.S., April 30 -- ClinicalTrials.gov registry received information related to the study (NCT07556874) titled 'Descriptive Analysis of Surgeries in Patients With Multiple Osteochondromas' on April 22.
Brief Summary: Multiple Osteochondromas (MO), also known as Multiple Cartilaginous Exostoses, is an autosomal dominant skeletal disorder with an incidence of approximately 1 in 50,000 in Western populations. Most cases are associated with pathogenic variants in the EXT1 and EXT2 genes, which lead to a systemic reduction of heparan sulfate, causing abnormalities in bone growth and other physiological processes.
Symptoms typically appear in childhood and include the development of bony protrusions often associated with pain due to compression o...