U.S., April 7 -- ClinicalTrials.gov registry received information related to the study (NCT07511582) titled 'Corticosteroids in Hyperinflammatory Phenotype of Critical Illness' on March 30.
Brief Summary: The goal of this clinical trial is to learn whether methylprednisolone improves outcomes in critically ill patients with a hyperinflammatory phenotype. It will also evaluate the safety of methylprednisolone at different doses.
The main questions it aims to answer are:
* Does methylprednisolone improve organ function compared with placebo?
* Does methylprednisolone reduce the risk of mortality within 30 days?
Researchers will compare high-dose methylprednisolone (160mg/d), low-dose methylprednisolone (80mg/d), and placebo (normal salin...