Clinical Trial: Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion.

U.S., Feb. 12 -- ClinicalTrials.gov registry received information related to the study (NCT07404696) titled 'Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion.' on Dec. 17, 2025.

Brief Summary: Background Approximately 15% of children have a Class II malocclusion, where the maxilla is positioned anterior to the mandible, and around 90% of these children also present with an increased overjet. Increased overjet is associated with a higher risk of dental trauma and psychosocial consequences such as bullying and reduced oral health-related quality of life (OHRQoL).

Functional orthodontic appliances (e.g., headgear-activator and Twin-block) have long be...