U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07755449) titled 'CLEAR (Cervical Lymphatic Exclusion in Adjuvant Radiation)' on July 30.
Brief Summary: The goal of this clinical trial is to learn if selectively omitting postoperative cervical irradiation is a safe and feasible treatment strategy for patients with resected, locally advanced squamous cell carcinoma of the head and neck (HNSCC) who underwent systematic neck dissection and have no high-risk nodal factors. The main questions it aims to answer are:
* Is the regional recurrence rate with selective omission of postoperative cervical irradiation non-inferior to the recurrence rate reported with standard complete nodal irradiation (6-8%)?...