Clinical Trial: Chlorophyllin for Reducing Oral Mucositis in Total Body Irradiation Prior to Transplant

U.S., July 17 -- ClinicalTrials.gov registry received information related to the study (NCT07709195) titled 'Chlorophyllin for Reducing Oral Mucositis in Total Body Irradiation Prior to Transplant' on July 11.

Brief Summary: The goal of this phase II, single-arm interventional clinical trial is to evaluate whether oral sodium copper chlorophyllin (CHL) can reduce the frequency and severity of oral mucositis in patients aged 12-65 years undergoing myeloablative total body irradiation (TBI) as part of conditioning before their first allogeneic hematopoietic stem cell transplantation (HSCT).

The main questions it aims to answer are:

Does oral chlorophyllin reduce the incidence of Grade III and IV oral mucositis by day +28 after HSCT? Does o...