Clinical Trial: Chemokine Receptors on CD8+ T Cells in Patients With Bipolar Disorder

U.S., Aug. 26 -- ClinicalTrials.gov registry received information related to the study (NCT07785167) titled 'Chemokine Receptors on CD8+ T Cells in Patients With Bipolar Disorder' on Aug. 20.

Brief Summary: This observational study investigates the expression profile of chemokine receptors and adhesion molecules in CD8+ T lymphocytes from individuals with Bipolar Disorder compared with healthy controls. The study focuses on CCR5 and CXCR3, which are involved in CD8+ T-cell migration toward the central nervous system, as well as the adhesion-related molecules PSGL-1, VLA-4, and LFA-1. Participants with Bipolar I or Bipolar II Disorder will be drug-naive or drug-free for at least 6 months and will be compared with healthy controls. Differenc...