U.S., Oct. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07861230) titled 'Characterization of the Tongue in Children With Obstructive Sleep-disordered Breathing' on Sept. 24.
Brief Summary: The tongue plays a key role in maintaining upper airway patency during sleep, mainly through the genioglossus, the principal pharyngeal dilator muscle. Its dysfunction may be linked to the development of obstructive sleep-disordered breathing (oSDB), a condition affecting more than one in ten children and associated with cardiovascular and cognitive consequences. Although adenotonsillectomy remains the treatment of choice, it fails in a substantial proportion of cases because of persistent obstruction at other sites, th...