U.S., Feb. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07399860) titled 'Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain' on Jan. 20.
Brief Summary: Hemorrhoidectomy is an effective surgical treatment for advanced hemorrhoidal disease but is often associated with significant postoperative pain, which may delay recovery. One of the main contributors to pain after hemorrhoidectomy is spasm and increased tone of the internal anal sphincter.
This randomized, double-blind, placebo-controlled clinical trial evaluates whether preoperative injection of botulinum toxin type A into the internal anal sphincter, performed seven days before hemorrhoidectomy, can reduce postoperative pain comp...